Fig. 1: Mitochondrial DNA (mtDNA) deletion profiles in muscle samples, comparing patients and controls.
From: Improved detection of mitochondrial DNA instability in mitochondrial genome maintenance disorders
Individuals were subdivided into four groups according to age. A Circos representative of one individual is shown for each group. N = number of patients/group. Selected parameters between patients compared to controls are represented as boxplots: deletion number, length of breakpoint repeats, heteroplasmy levels, maximum cumulative percentage of deletions. Statistical significances are *p < 0.05, **p < 0.01, ***p < 0.001.
