Fig. 2: Slc68a−/y mouse model echocardiographic data 3 and 9 months demonstrates preserved systolic function, LV chamber dilation, and increased LV was thickness. | Genetics in Medicine

Fig. 2: Slc68a−/y mouse model echocardiographic data 3 and 9 months demonstrates preserved systolic function, LV chamber dilation, and increased LV was thickness.

From: X-linked creatine transporter deficiency results in prolonged QTc and increased sudden death risk in humans and disease model

Fig. 2

Scatter plots demonstrate echocardiographic demographic data including: (a) age, (b) weight as well as systolic function, (c) FS (%) and chamber structural parameters, (d) LV mass index, (e) LVIDd, (f) LVIDs, (g) LVPWDd, and (h) LVPWDs in both Slc68a−/y mice and controls. Imaging was performed under light sedation. Data are presented as mean ± SD, and significance was assessed using Mann–Whitney test. FS fractional shortening, LV left ventricular, LVIDd LV internal dimension (diastole), LVIDs LV internal dimension (end-systole), LVPWDd LV posterior wall dimension (diastole), LVPWDs LV posterior wall dimension (systole).

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