Table 2 MAC (mean ± SD) comparison in the US samples

From: Collective effects of common SNPs and risk prediction in lung cancer

SNPs set

Number

MAC controls (n = 968)

MAC cases (n = 1209)

Total loci

511,547

0.24754 ± 1.17E-03

0.24779 ± 9.35E-04***

r2 = 0.05

21,974

0.15483 ± 1.70E-03

0.15528 ± 1.67E-03***

r2 = 0.1

45,471

0.16036 ± 1.28E-03

0.16073 ± 1.18E-03***

r2 = 0.2

88,752

0.17955 ± 1.09E-03

0.17994 ± 9.15E-04***

r2 = 0.3

130,675

0.19701 ± 1.01E-03

0.19736 ± 8.09E-04***

r2 = 0.4

174,501

0.21151 ± 9.97E-04

0.21182 ± 7.84E-04***

r2 = 0.5

222,223

0.22287 ± 1.01E-03

0.22318 ± 7.88E-04***

r2 = 0.6

271,731

0.23141 ± 1.04E-03

0.23169 ± 7.97E-04***

r2 = 0.7

320,982

0.23803 ± 1.05E-03

0.23828 ± 8.25E-04***

r2 = 0.8

366,757

0.24275 ± 1.09E-03

0.24301 ± 8.47E-04***

r2 = 0.9

407,569

0.24551 ± 1.11E-03

0.24575 ± 8.76E-04***

r2 = 1

492,053

0.24894 ± 1.16E-03

0.24919 ± 9.25E-04***

  1. The t test was performed to get P-values, and boldface indicates significant P-values. ***P < 0.001, **P < 0.01, and *P < 0.05