Table 1 Cuticular hydrocarbons (CHCs) that showed significant intraspecific differences in accumulation due to having only a single allele within the region spanned by a deficiency (Df), i.e., due to being hemizygous

From: The genetic basis of female pheromone differences between Drosophila melanogaster and D. simulans

  

CHC Name a

n -C21

n -C22

n -C23

n -C24

n -C25

n -C27

9-T

7-T

5-T

7-P

5-P

9-H

7-H

7-N

9,13-PD

7,11-PD

9,13-HD

7,11-HD

7,11-ND

23-Br

25-Br

26-Br

27-Br

29-Br

31-Br

  

Carbons b

21

22

23

24

25

27

23

23

23

25

25

27

27

29

25

25

27

27

29

23

25

26

27

29

31

  

Features b

–

–

–

–

–

–

1D

1D

1D

1D

1D

1D

1D

1D

2D

2D

2D

2D

2D

B

B

B

B

B

B

Df c

Cyto.d

Genes e

                         

Df(3L)ED4457 [1]

67E2;68A7

98

                  

***

      

Df(3L)ED4486 [2]

69E6;69F6

49

          

**

 

**

            

Df(3L)fz-GF3b

70C1;70D2

45

      

**

    

**

          

**

  

Df(3L)ED4782

75F2;76A1

22

           

****

  

**

          

Df(3L)XS533 [3]

76B4;77B

161

 

**

  

****

     

***

          

**

   

Df(3L)ri-79c

77B;77F3

120

  

***

             

*

***

       

Df(3L)BSC284 [4]

78F1;79A3

16

***

          

*

     

***

       

Df(3L)BSC223 [5]

79B2

8

               

***

         

Df(3L)BSC249

79B2

8

         

****

    

***

          

Df(3L)ED5017

80A4;80C2

23

  

***

 

**

  

****

***

  

***

          

**

  

Df(3R)ME15

81F3;82F4

101

****

 

****

 

***

                    

Df(3R)3-4

82F5;82F7

15

         

**

               
 

82F8;82F10

8

                   

**

     

Df(3R)ED5156

82F8;82F10

8

                   

*

     
 

82F10;83A4

26

     

**

     

*

             

Df(3R)Exel6144

83A6;83B3

14

              

**

          

Df(3R)ED5177 [7]

83B6

5

           

*

             

Df(3R)p712

84D4;85A4

159

 

*

                       

Df(3R)ED5330 [8]

85A5;85D1

83

                  

****

      

Df(3R)BSC38

85F1;86C1

69

**

                        

Df(3R)M-Kx1

86C7;86D8

61

     

*

                   
 

86D9;87B5

139

    

****

    

****

               

Df(3R)T-32 [9]

86D9;87B5

139

    

****

    

**

               
 

87B1;87C1

82

 

*

****

****

       

***

     

**

     

*

 

Df(3R)ED5644

88A4;88C9

77

         

****

    

***

          

Df(3R)ED5664

88D1;88E3

57

       

*

 

****

               

Df(3R)BSC471 [10[

88E3;88E5

9

***

*

***

        

***

   

****

 

**

 

***

   

**

 

Df(3R)P115

89B7;89E7

97

              

*

     

**

    

Df(3R)ED5780

89E11;89F4

31

                  

****

      

Df(3R)Cha7 [11]

91B1;91F1

71

***

 

****

     

*

***

 

***

       

*

***

    
 

91F1;91F5

14

 

***

 

**

                     

Df(3R)Dl-BX12 [12]

91F1;91F5

14

 

**

 

**

                     
 

91F6;92B3

63

                        

***

Df(3R)e-R1 [14]

93B6;93C5

31

             

**

           

Df(3R)e-GC3

93D3;94A4

119

           

**

   

**

         

Df(3R)BSC56

94E1;94E9, 94F1;94F2

30

 

**

                 

**

     

Df(3R)Exel9012 [15]

94E9;94E13

15

           

**

             

Df(3R)crb87-5

96A7

3

 

***

                       

Df(3R)ED6220 [19]

96A18;96C3

94

  

***

 

***

   

***

        

*

**

      

Df(3R)Exel6203 [20]

96E2;96E6

9

           

*

  

*

          

Df(3R)BSC321

96E6;96E9

13

***

       

**

***

        

*

      

Df(3R)BSC140 [21]

96F1

2

     

*

     

***

  

***

          

Df(3R)3450

98E3;99A8

82

         

****

 

****

  

**

          

Df(3R)BSC547 [22]

99B5;99B6

5

**

      

***

   

***

             

Df(3R)L127

99C8;99E4

65

               

****

   

*

     

Df(3R)B81

99C8;99E4

65

               

***

   

***

     
 

99E4;100E1

181

    

**

***

                   

Df(3R)ED50003 [23]

100E1;100F5

6

       

***

***

*

    

**

          
  1. aCHC name abbreviations are shown; full names can be found in the legend of Fig. 2. The primary compounds that have historically been studied in this species pair have their name underlined
  2. bCHCs are ordered based on the number of carbons within the chain and whether the compound is a simple chain with no defining features (-), has one (1D) or two (2D) double bonds, or a branch in the carbon chain (B) with a 2-methyl group. Note that no lines were significant for compounds 6-T, 7,11-He + D, or n-C29, and so those columns are not shown
  3. cThe italicized number in brackets [#] next to the deficiency name is the same as that overlaid on the biochemical pathway in Fig. 4, and is shown to facilitate comparison. Numbering is based on compounds listed in Table 2, and thus in Table 1 not all deficiencies have a number and not all numbers are listed
  4. dThe cytological region (Cyto.) underlying the significant effect was determined through comparison among overlapping significant and/or non-significant deficiencies. Since cytological breakpoints are not precise for all deficiencies, in some cases we assumed that the significant region was at the margin where a significant and non-significant deficiency both ended. Note that some deficiencies are divided into multiple rows, where the region of overlap indicates that some compounds are affected by one region of the deficiency, while others are affected by a different region. CHCs that had a significant change due to hemizygosity for that region have their P-value represented by * ≤ 0.05, ** ≤ 0.005 *** ≤ 0.0005 **** ≤ 0.0001; all others were not statistically significant. Compounds that significantly increased in sim/Df have their P-value representation underlined; those that decreased are not underlined
  5. eThe number of protein-coding genes (Genes) within each region was determined using CytoSearch in FlyBase