Fig. 3 | Heredity

Fig. 3

From: The fitness cost of mismatch repair mutators in Saccharomyces cerevisiae: partitioning the mutational load

Fig. 3

Distributions of fitness in haploid wild types (a) and mmr mutators (b). We measured the fitnesses of 327 wild type and 313 mmr clones. Fitnesses were measured in competition with an MMR+ YFP+ reference strain otherwise isogenic to the wild type, as described in “Methods” section. Dashed vertical lines indicate the mean. The load is ~0 for wild types; for mmr mutators it is ~1.7%. QQ plots of the fitness distributions are shown as insets. The two distributions differ significantly (Kolmogorov–Smirnov test, p < 10−8)

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