Fig. 1: M.TB population diversity from a host sample.
From: The population genomics of within-host Mycobacterium tuberculosis
An example of a clinical sample, demonstrating how a consensus sequence-based analysis neglects low-frequency variants (which are expected to constitute the majority of within-host variation). Each star in the clinical sample represents a unique variant. In this example, only one of the four variants would be represented in the consensus.
