Table 6 Top ten methylation sites with the strongest effects from whole-methylome prediction using Bayes-B.
Methylation sitea | Chromosome: base pair | Relation to island | Gene name | Relation to gene | Regulatory feature group | Effect |
|---|---|---|---|---|---|---|
cg24147543 | 6: 32554481 | S shelf | Major histocompatibility complex, class II, DR beta 1 (HLA-DRB1) | Body | NA | −0.00033 |
cg10132543 | 11: 68609520 | N shore | Carnitine palmitoyltransferase 1A (CPT1A) | TSS200 | NA | −0.00022 |
cg26572452* | 8: 129115055 | Open sea | Long intergenic nonprotein coding RNA 977 (LINC00977) | 129.22 Kb upstream | Unclassified | −0.00021 |
cg04362887 | 14: 91285234 | S shelf | Coiled-coil domain containing 88C (CCDC88C) | 91.271 Kb downstream | NA | −0.00017 |
cg01695533 | 16: 86542905 | Island | Forkhead box F1 (FOXF1) | TSS1500 | Unclassified cell type specific | −0.00017 |
cg19741273 | 14: 101123263 | S shore | Chromosome 14 open reading frame 70 (C14orf7) | TSS1500 | NA | −0.00017 |
cg09717927 | 13: 112630399 | N shore | ATP11A upstream neighbor (ATP11AUN) | 112.26 Kb upstream | NA | −0.00017 |
cg05726118* | 3: 41265374 | Open sea | Catenin beta 1 (CTNNB1) | 5’UTR | NA | −0.00017 |
cg18858739* | 1: 167426278 | S shore | CD247 molecule (CD247) | Body | Promoter associated cell type specific | −0.00017 |
cg12853199* | 4: 13356876 | Open sea | Member RAS oncogene family (RAB28) | 13.361 Kb downstream | NA | −0.00016 |