Table 7 Top ten methylation sites with the strongest effects from whole-genome/methylome prediction using Bayes-B.
Methylation sitea | Chromosome: base pair | Relation to Island | Gene name | UCSC reference gene group | Regulatory feature group | Effect |
|---|---|---|---|---|---|---|
cg10132543 | 11: 68609520 | N shore | Carnitine palmitoyltransferase 1A (CPT1A) | TSS200 | NA | −0.00978 |
cg15821716 | 8: 71581642 | Island | XK related 9 (XKR9); Lactamase beta 2 (LACTB2) | 5′UTR and 1st Exon; TSS200 | Promoter associated | −0.00814 |
cg00393182 | 1: 1.55E+08 | N shore | Sequence similarity 189 member B (FAM189B) | Body | NA | −0.00739 |
cg24147543 | 6: 32554481 | S shelf | Major histocompatibility complex, class II, DR beta 1 (HLA-DRB1) | Body | NA | −0.00731 |
cg18106803 | 1: 2303963 | N shore | MORN repeat containing 1 (MORN1) | Body | NA | −0.00708 |
cg09853238* | 6: 149532290 | Open sea | Peptidylprolyl isomerase like 4 (PPIL4) | 13.7 Kb downstream | Unclassified cell type specific | −0.00638 |
cg17360552 | 6: 32725332 | Open sea | Major histocompatibility complex, class II, DQ beta 2 (HLA-DQB2) | Body | NA | −0.00585 |
cg18858739* | 1: 167426278 | S shore | CD247 molecule (CD247) | Body | Promoter associated cell type specific | −0.00576 |
cg15266530 | 7: 134516810 | Open sea | Caldesmon 1 (CALD1) | 5′UTR | NA | −0.00524 |
cg26572452* | 8: 129115055 | Open sea | Long intergenic nonprotein coding RNA 977 (LINC00977) | 101 Kb upstream | Unclassified | −0.00516 |
