Fig. 5: Functional enrichment of differentially regulated genes between ecotypes.
From: Gene expression and alternative splicing contribute to adaptive divergence of ecotypes
A GO terms enriched among DE genes up-regulated in the dune ecotype (N = 2480). B Venn diagram showing number of transcripts that are differentially expressed (DE), differentially spliced (DS), or both (DE ∩ DS) between ecotypes (FDR < 0.05). Significance of overlap between DE genes and DS gene sets was assessed with a hypergeometric test (p < 0.001; Representation Factor, RF = 1.4; RF values > 1 indicate more overlap than expected due to chance). C GO terms enriched among DS genes (N = 1038). D GO terms enriched among genes that are both DE and DS (N = 232). GO terms are arranged top to bottom by decreasing enrichment test significance (decreasing dot size) in panels A, C, and D. Some GO terms are abbreviated due to space: “…endoplasmic reticulum membrane”=“integral component of cytoplasmic side of endoplasmic reticulum membrane”; “embryo dev. ending in seed dorm.”=“embryo development ending in seed dormancy”; “glycine decarboxylation…”=“glycine decarboxylation via glycine cleavage system”.
