Table 1 Patterns of variation between mouse subspecies in binding sites of transcriptional regulators upstream of translation genes.

From: Stem cell transcriptional profiles from mouse subspecies reveal cis-regulatory evolution at translation genes

TF

OR

ANOVA p

p-adj

Aebp2

0.244

1.43E-05

0.0054

Tlx1

0.328

1.76E-05

0.0054

Ctr9

1.470

1.61E-04

0.0329

Rfx6

2.635

2.15E-04

0.0330

Hoxa11

2.649

5.76E-04

0.0694

Mllt3

0.486

7.33E-04

0.0694

Ehmt2

4.204

7.91E-04

0.0694

  1. Shown are results of analysis of normalized sequence divergence, at the regions upstream of genes, between M. m. castaneus on the one hand and M. m. musculus and M. m. domesticus on the other. Each row reports results of an ANOVA testing for an interaction effect between two factors on the divergence metric: position of sequence variants in binding sites of the indicated transcriptional regulator and gene membership in the translation GO term (see Fig. 3A). Normalized divergence was calculated as the number of sites divergent between M. m. castaneus and a given M. musculus relative, normalized by the number of sites polymorphic within the populations. The second and third columns report the odds ratio (OR) and nominal p-value, respectively, and the third reports the p-value after Benjamini-Hochberg correction for multiple testing. OR > 1 indicates enrichment of normalized divergence at regulator binding sites relative to the other three categories, and OR < 1 indicates depletion. Full results are shown in Table S7.
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