Fig. 3: Mitonuclear double mutant fitness.

A Box plots of fitness data for G0 isp-1 (yellow) and ctb-1 (orange) single mutants and the isp-1 IV; ctb-1 M double mutant (green) relative to N2 (same data as in Fig. 1). B A box plot of G60 isp-1 and ctb-1 single mutant RC lines and isp-1 IV; ctb-1 M double mutant RC lines relative to their respective G0 ancestral background (same data as in Fig. 2). Note the broken y-axis and change in scale relative to (A). Each plot was created using average relative fitnesses from eight independently evolving replicate lines. Single points denote statistical outliers. All data in panels A and B are from animals experiencing the wildtype facultatively outcrossing mating system.