Fig. 6: Outcome of WGBS methylome analysis.
From: Molecular memory of Flavescence dorée phytoplasma in recovering grapevines
a Plot of principal component analysis displaying the distinction between REC and H methylomes. b, c Venn diagrams showing the number of hyper- (b) and hypomethylated (c) genes interested by CpG differential methylation at the level of gene body, 1 and 5 kb upstream regions of REC genes. d Enrichment of GO biological process categories for the group of 288 genes CpG hypermethylated at the promoter level matching the RNAseq data (Supplementary Table S10). The significant enriched GO biological processes terms were identified using Cytoscape with the BINGO plug-in and listed according to their enrichment P‐value (P < 0.05). e Merger between WGBS and RNAseq data: the heat map highlights the differential methylation levels of a group of genes CpG hypermethylated at the promoter level (left) in comparison with the downregulation of the corresponding transcripts (right)
