Table 3 Typing results between the Luminex method and NGS-based HLA typing for all inconsistent samples. Bold font corresponds to the typing results from NGS-based HLA typing

From: HLA-VBSeq v2: improved HLA calling accuracy with full-length Japanese class-I panel

 

HLA typing

HLA calling

Dataset

Sample

NGS-baseda

Luminex

HLA-VBSeq

HLA-VBSeq v2

HLA*PRG:LA

SJS

SJS01

B*59:04

B*59:01

B*59:01

B*59:01

B*59:04

SJS02

C*07:06

C*07:01

C*07:06

C*07:06

C*07:01

SJS03

C*08:22

C*08:01

C*08:22

C*08:22

C*08:01

SJS04

C*04:82

C*04:01

C*04:01

C*04:82

C*04:01

THC

THC01

A*02:15N

A*02:07

A*02:15N

A*02:07

A*02:07

THC02

A*11:02

A*11:01

A*11:02

A*11:01

A*11:02

THC03

B*07:169

B*07:02

B*07:02

B*07:02

B*07:02

THC04

C*08:22

C*08:01

C*08:22

C*08:22

C*08:01

THC05

C*08:22

C*08:01

C*08:01

C*08:22

C*08:01

THC06

C*04:82

C*04:01

C*04:01

C*04:82

C*04:01

THC07

C*04:82

C*04:01

C*04:82

C*04:82

C*04:01

THC08

C*04:82

C*04:01

C*04:01

C*04:82

C*04:01

THC09

C*04:82

C*04:01

C*04:01

C*04:82

C*04:01

THC10

C*04:82

C*04:01

C*04:01

C*04:82

C*04:01

THC11

C*04:82

C*04:01

C*04:82

C*04:82

C*04:01

THC12

C*04:82

C*04:01

C*04:01

C*04:82

C*04:01

THC13

C*04:82

C*04:01

C*04:01

C*04:82

C*04:01

THC14

C*04:82

C*04:01

C*04:01

C*04:82

C*04:01

THC15

C*04:82

C*04:01

C*04:01

C*04:82

C*04:01

  1. aThese typing results were used as the “true” types