Fig. 1: Clinical assessment of the VTE patient.
From: Venous thromboembolism is caused by prothrombin p.Arg541Trp mutation in Japanese individuals

A Right ventricular dysfunction found on echocardiography of the proband expressing the prothrombin p.R541W variant. RV, right ventricle; LV, left ventricle. B A thoracic CT scan showing multiple pulmonary embolisms (indicated by arrows) from the lobe branch level of the pulmonary artery to the peripheral part of the main pulmonary artery on both sides. C Venous ultrasonography of the left leg showing echogenic noncompressable thrombi on the center side of the left popliteal vein. D Schematic distribution of deep vein thrombi on the center side of the left popliteal vein and in the portion from the left popliteal vein to the center side of the peroneal vein, as indicated by arrows.