Fig. 1: Diagram of CHAMP1 variants.
From: Intellectual disability and microcephaly associated with a novel CHAMP1 mutation
Diagram of previously reported CHAMP1 variants (upper panel) and the mutation identified in this case (lower panel, underlined). CHAMP1 consists of five zinc-finger domains (ZNF) and several motifs; SPE (consensus: PxxSPExxK; dots), WK (SPxxWKxxP; diagonal lines), and FPE (FPExxK; grey bar).
