Table 1 Baseline characteristics

From: Higher plasma leptin levels are associated with reduced left ventricular mass and left ventricular diastolic stiffness in black women: insights from the Genetic Epidemiology Network of Arteriopathy (GENOA) study

Variables

Men (n = 324)

Women (n = 848)

p Value

Age, years

63.4 ± 8.9

62.8 ± 9.4

0.341

BMI, kg/m2

29.1 ± 4.8

32.4 ± 6.8

<0.001

Systolic BP, mmHg

136 ± 20

140 ± 21

0.007

Diastolic BP, mmHg

81 ± 10

78 ± 11

<0.001

Heart rate, bpm

64 ± 12

66 ± 11

0.002

Hypertension, %

74.1%

80.5%

0.015

Diabetes, %

26.9%

28.3%

0.621

Dyslipidemia, %

57.1%

46.6%

0.001

Coronary artery disease, %

7.4%

3.9%

0.012

Current smoker, %

20.4%

11.0%

<0.001

Estimated GFR, mL/min

94 ± 14

84 ± 19

0.014

Leptin, ng/ml

8.8 (5.2–13)

30.9 (21.7–42.6)

<0.001

Log-Leptin, ng/ml

2.14 ± 0.78

3.37 ± 0.58

<0.001

LVDd, mm

53.4 ± 4.5

50.2 ± 3.9

<0.001

LVPWd, mm

8.5 ± 1.2

8.0 ± 1.2

<0.001

RWT

0.32 ± 0.05

0.32 ± 0.05

0.603

LV mass, g

176 ± 43

148 ± 37

<0.001

LV mass index, g/m2.7

37.4 ± 9.3

39.0 ± 10.1

0.012

LVEF, %

60.7 ± 5.0

62.8 ± 5.0

<0.001

LVFS, %

32.8 ± 3.6

34.2 ± 3.6

<0.001

LVMFS, %

12.8 ± 2.6

12.4 ± 2.5

0.022

E wave velocity, cm/s

46.9 ± 13.7

47.5 ± 14.1

0.493

A wave velocity, cm/s

59.0 ± 13.0

61.1 ± 13.7

0.019

E/A

0.81 ± 0.24

0.80 ± 0.26

0.578

DT, ms

175 ± 41

174 ± 43

0.601

IVRT, ms

96 ± 18

94 ± 16

0.038

DWS

0.35 ± 0.05

0.36 ± 0.05

0.004

LAD, mm

36.4 ± 5.0

35.2 ± 5.0

<0.001

  1. BP blood pressure, DT deceleration time, DWS diastolic wall strain, IVRT isovolumic relaxation time, LA left atrium, LAD left atrium dimension, LVDd LV dimension at end-diastole, LVEF LV ejection fraction, LVFS LV fractional shortening, LVMFS LV midwall fractional shortening, LVPWd LV posterior wall thickness at end-diastole, RWT relative wall thickness
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