Table 1 Clinical characteristics of the subjects according to the severity of OSA

From: Impact of obstructive sleep apnea on long-term blood pressure variability in Japanese men: a cross-sectional study of a work-site population

 

Non-OSA

Mild-to-moderate OSA

Severe OSA

Number of subjects (n, %)

1414 (85.6)

131 (7.9)

108 (6.5)

Age (years)

44.6 ± 0.2

47.2 ± 0.7*

47.4 ± 0.7*

BMI (kg/m2)

23.5 ± 0.1

26.1 ± 0.3*

28.0 ± 0.5*

SBP (mm Hg)

120.9 ± 0.3

125.2 ± 1.1*

128.0 ± 1.1*

DBP (mm Hg)

78.2 ± 0.3

80.8 ± 0.8*

83.5 ± 1.0*

SD of SBP (mm Hg)

7.5 ± 0.1

6.8 ± 0.1

7.8 ± 0.4

CV of SBP (%)

6.2 ± 0.1

5.5 ± 0.3*

6.1 ± 0.3

SD of DBP (mm Hg)

5.7 ± 0.1

5.3 ± 0.2

6.0 ± 0.3

CV of DBP (%)

7.4 ± 0.1

6.6 ± 0.3*

7.3 ± 0.3

LDL-cholesterol (mg/dl)

127.4 ± 0.8

131.6 ± 2.5

128.4 ± 2.8

HDL-cholesterol (mg/dl)

55.5 ± 0.4

52.7 ± 1.2

50.0 ± 1.1*

Triglyceride (mg/dl)

151.0 ± 3.2

180.0 ± 18.9*

179.4 ± 9.9

AST (IU/l)

23.1 ± 0.2

24.7 ± 0.9

26.6 ± 1.4*

ALT (IU/l)

27.4 ± 0.5

30.4 ± 1.7

35.7 ± 2.5*

γ-GTP (IU/l)

44.1 ± 1.1

55.6 ± 5.2*

52.6 ± 3.7

eGFR (ml/min/1.73 m2)

82.8 ± 0.4

80.2 ± 1.2

79.8 ± 1.0*

Uric acid (mg/dl)

5.9 ± 0.03

6.1 ± 0.1

6.2 ± 0.1

Glucose (mg/dl)

96.7 ± 0.6

101.5 ± 2.1*

103.3 ± 2.2*

HbA1c (%)

5.6 ± 0.02

5.8 ± 0.1*

6.0 ± 0.1*

Habitual alcohol intake (n, %)

834 (59)

85 (65)

64 (59)

Current smoking (n, %)

665 (47)

58 (44)

55 (51)

Hypertension (n, %)

254 (18.0)

41 (31.3)*

48 (44.4)*

Antihypertensive use (n, %)

140 (9.9)

27 (20.6)*

31 (28.7)*

  1. Values are given as the means ± SE or as a number (n, %)
  2. OSA obstructive sleep apnea, SBP systolic blood pressure, DBP diastolic blood pressure, AST aspartate transaminase, ALT alanine transaminase, γ-GTP gamma-glutamyl transpeptidase, LDL low-density lipoprotein, HDL high-density lipoprotein, eGFR estimated glomerular filtration rate, HbA1c hemoglobin A1c
  3. *P   < 0.05 vs non-OSA by Dunnett’s multiple comparison test or by Bonferroni-corrected chi-square test
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