Fig. 6 | Hypertension Research

Fig. 6

From: Effects of the novel nonsteroidal mineralocorticoid receptor blocker, esaxerenone (CS-3150), on blood pressure and urinary angiotensinogen in low-renin Dahl salt-sensitive hypertensive rats

Fig. 6

Renal oxidative stress in DSS rats. a Representative micrographs of 4-hydroxynonenal (4-HNE)-stained renal sections. Original magnification, ×200. b Quantitative analysis of the 4-HNE-positive area in the renal interstitium. c mRNA expression of p22phox. d mRNA expression of gp47phox. The ΔΔCt value was calculated using data from the NS + vehicle group. *P < 0.05 vs. NS + vehicle. #P < 0.05, HS + vehicle vs. HS + losartan or HS + esaxerenone. †P < 0.05, HS + losartan vs. HS + esaxerenone

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