Fig. 2 | Hypertension Research

Fig. 2

From: Effect of a novel nonsteroidal selective mineralocorticoid receptor antagonist, esaxerenone (CS-3150), on blood pressure and renal injury in high salt-treated type 2 diabetic mice

Fig. 2

Effects of esaxerenone (EXR) and spironolactone (SPL) on glomerular injury. Renal histopathological changes were evaluated by examining periodic acid-Schiff (PAS) staining. a Representative images of PAS-stained renal sections. b The PAS-positive area within total glomerular area (purple color staining). c Mean glomerular diameters expressed as fold changes with C57BL/6 group. NS, normal salt diet; HS, high salt diet; C57BL/6, C57BL/6 mice; KK-Ay, KK-Ay mice. aP < 0.05 vs. KK-Ay + HS

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