Table 1 Characteristics of studies included in the meta-analysis

From: Are the cardiovascular outcomes of participants with white-coat hypertension poor compared to those of participants with normotension? A systemic review and meta-analysis

First Author, Publication Year

Country

Txt Incl

Number of participants

Men (%), and Age (SD)

OBP Threshold, mmHg

Out-of-office BP Threshold, mmHg

Follow-up, years

Outcomes

Verdecchia P [10] 1994.

Italy

No

1,187 (205 NT, 228 WCH)

NT: 56%, 45(15) WCH: 47%, 50(12)

140/90

Daytime ABP 131/86 in women, 136/87 in men

3.2

1

Strandberg TE [23] 2000.

Finland

No

536 (259 NT, 18 WCH)

NT: 100%, 46(4) WCH: 100%, 48(4)

140/90 by nurse160/95 by physician

140/90 by nurse 160/95 by physician

21

1, 4

Kario K [11] 2001.

Japan

No

958 (147 NT, 236 WCH) All age ≥ 50 years

NT: 38%, 68(9.7) WCH: 34%, 72(9.9)

140/90

24-hr ABP 130/80

3.5

1, 2, 3, 4

Ugajin T [16] 2005.

Japan

No

972 (649 NT, 128 WCH)

NT: 32.4%, 55.8(8.5) WCH: 42.2%, 57(9.5)

140/90

HBP 135/85

8

5

Fagard RH[34 2005

Belgium

Yes

391 (136 NT, 87 WCH) 71(9) years, 40%

NT: 48%, 69.2(7.9) WCH: 28%, 70.0(8.2)

140/90

daytime ABP 135/85

10.9

1

Pierdomenico SD [26] 2008.

Italy

No

1,732 (305 NT, 399 WCH)

NT: 40.7%, 47.7(13.7) WCH: 47.1%, 49.9(13.9)

140/90

daytime ABP 135/85

6.4

1

Sung SH [25] 2013.

Taiwan

No

1,257 (250 NT, 153 WCH)

NT: 48%, 48(13) WCH: 51%, 51(13)

140/90 for WCH 120/80 for NT

daytime ABP 135/85

15

1, 4

Cacciolati C [13] 2013.

France

Yes

1,481 (192 NT, 83 WCH)

NT: 31.2%, 77.6(3.4) WCH: 34.9%, 78.4(4.0)

140/90

HBP 135/85

1

5

Asayama K [24] 2014.

International

No

8,237 (4,988 NT, 881 WCH)

NT: 44.5%, 45.7(15.1) WCH: 54.1%, 59.3(13.8)

140/90

Daytime ABP 135/85, Nighttime ABP: 120/70, and 24-hr ABP: 130/80

11.1

1, 2, 3, 4

Stergiou GS [12] 2014.

International

Yes

6,458 (2,984 NT, 695 WCH)

NT: 38.7%, 53.7(13.6) WCH: 46.6%, 58.8(12.1)

140/90

HBP 135/85

8.3

1, 4

Sivén SS [14] 2016.

Finland

No

944 (528 NT, 142 WCH) 54.1(7.4), 45.7%

NT: 61%, 52.8(6.8) WCH: 48.6%, 55.3(7.8)

140/90

HBP 135/85 (7 days)

11

5

  1. Home blood pressure (HBP) in Cacciolati C et al. was measured 6 times per day, 3 in the morning and 3 in the evening, for 3 consecutive days within 2 weeks. Country in Asayama K et al. included Denmark, Japan, Belgium, Sweden, Uruguay, China, Ireland, the Russian Federation, Poland, and Venezuela, and that in Stergiou GS et al. included Japan, Finland, Greece, and Uruguay. Outcomes 1 to 5 refer morbidly and mortality on cardiovascular, stroke, and cardiac diseases, all-cause mortality, and deterioration to sustained hypertension, respectively. Txt Incl, patients with antihypertensive drug treatment is included; NT, normotension; WCH, white-coat hypertension; ABP; ambulatory blood pressure; OBP; office blood pressure