Fig. 2

Medial layer of the coronary artery. Shown are rings (examples of projections obtained from confocal microscopy images, ×20, zoom 2) (a), cell nuclei (examples of projections obtained from confocal microscopy images, ×20, zoom 8) (b), and the composition of the medial layer (medial thickness, medial cell number, and medial cell density) (c) of the coronary artery from Wistar Kyoto rats (WKY group), spontaneously hypertensive rats (SHRs; SHR group), SHRs treated with dronedarone (SHR-D group), and SHRs treated with hydralazine (SHR-H group). N = 9 rats for each experimental group. The data are expressed as the mean ± SEM. Statistically significant differences among the WKY, SHR, SHR-D, and SHR-H groups are shown (∗P < 0.05 versus WKY; ∗∗∗P < 0.001 versus WKY; #P < 0.05 versus SHR; ##P < 0.01 versus SHR; §P < 0.05 versus SHR-D)