Table 2 Creatinnine, Na+, K+, Urea, and Selenium in serum and urine and their relative clearances

From: Binge drinking affects kidney function, osmotic balance, aldosterone levels, and arterial pressure in adolescent rats: the potential hypotensive effect of selenium mediated by improvements in oxidative balance

Parameters

C

BD

CSe

BDSe

Serum

Creatinine (mg/dL)

0.25 ± 0.015

0.26 ± 0.005

0.22 ± 0.015

0.28 ± 0.020

Na + (mmol/L)

139.25 ± 1.32

150.5 ± 1.02***

138 ± 1

146.8 ± 1.08•••

K + (mmol/L)

6.37 ± 0.14

5.53 ± 0.23*

6.25 ± 0.18

5.75 ± 0.09

Urea (mmol/L)

41.17 ± 1.81

36.77 ± 1.76

38.17 ± 0.90

34.52 ± 1.65

Selenium (µg/L)

205.35 ± 6.8

178.70 ± 5.7**, aaa

335.32 ± 8.0cc

235.26 ± 6.4•••

Urine

Creatinine (mg/dL)

15.09 ± 1.29

18.39 ± 1.75

13.34 ± 0.73

15 ± 1.31

Na + (mmol/L)

26.83 ± 1.30

17.75 ± 2.8

25.5 ± 1.24

18.75 ± 1.28

K + (mmol/L)

46.88 ± 4.99

47.61 ± 3.33

39.25 ± 1.82

41.47 ± 2.20

Urea (mmol/L)

625.7 ± 33.6

749.4 ± 35.7a

610.9 ± 35.7

603.5 ± 18.9

Selenium (ng/day)

440 ± 24

180 ± 10***

540 ± 20ccc

150 ± 10•••

Clearances (CL)

CL Na + /CL creatinine

0.0031 ± 1.59 × 10−4

0.0015 ± 9.52 × 10−5***

0.0029 ± 1.425 × 10−4

0.0017 ± 1.25 × 10−4•••

CL K + /CL creatinine

0.113 ± 5.8 × 10−3

0.151 ± 6 × 10−3***

0.11 ± 5.8 × 10−3

0.14 ± 6 × 10−3••

CL Urea/CL creatinine

0.23 ± 0.01

0.25 ± 0.01

0.24 ± 0.01

0.25 ± 0.01

CL Se/CL creatinine

0.019 ± 8.6 × 10−4

0.008 ± 2.8 × 10−4***, aa

0.028 ± 1.1 × 10−3ccc

0.012 ± 4.1 × 10−4•••

  1. The results are expressed as mean ± SEM and analysed by a multifactorial analysis of variance (one-way ANOVA) followed by the Tukey's test. The number of animals in each group is 8. Statistical difference between groups is expressed as p value and is indicated by * when C versus BD groups were compared; by when CSe versus BDSe groups were compared; by a when BD versus BDSe groups were compared; and by c when C versus CSe groups were compared
  2. C control group, BD binge drinking group, CSe control selenium supplemented group, BDSe binge drinking selenium supplemented group