Table 1 Clinical and demographic characteristics and blood pressure measurements at the orthostatic test
Clinical and Demographic Characteristics | |||
|---|---|---|---|
OH + (n = 53) | OH− (n = 60) | p value | |
Age [years] | 68 ± 8 | 62 ± 11 | <0.01 |
Female sex [n (%)] | 14 (26) | 18 (30) | 0.67 |
Weight [kg] | 72 ± 12 | 71 ± 11 | 0.73 |
Height [m] | 1.69 ± 0.1 | 1.69 ± 0.1 | 0.72 |
Body Mass Index [kg/m2] | 25 ± 3.6 | 24.6 ± 3.1 | 0.48 |
PD duration [years] | 7 ± 4 | 6 ± 4 | 0.21 |
Hoehn & Yahr stage 1 [n (%)] | 6 (11) | 9 (15) | 0.90 |
Hoehn & Yahr stage 1.5 [n (%)] | 10 (19) | 13 (22) | 0.51 |
Hoehn & Yahr stage 2 [n (%)] | 15 (28) | 16 (27) | 0.82 |
Hoehn & Yahr stage 2.5 [n (%)] | 11 (21) | 16 (27) | 0.63 |
Hoehn & Yahr stage 3 [n (%)] | 10 (19) | 5 (8) | 0.12 |
Hoehn & Yahr stage 4 [n (%)] | 1 (2) | 1 (2) | 0.91 |
Presence of motor fluctuations [n (%)] | 27 (51) | 23 (38) | 0.26 |
LEDD [mg] | 756 ± 403 | 636 ± 333 | 0.10 |
Essential hypertension [n (%)] | 20 (38) | 12 (20) | 0.04 |
Anti-hypertensive drugs [n (%)] | 4 (8) | 12 (20) | 0.07 |
Anti-hypotensive drugs [n (%)] | 13 (25) | 0 (0) | <0.01 |
Anti-hypotensive plus anti-hypertensive drugs [n (%)] | 16 (30) | 1 (2) | <0.01 |
Blood pressure measurement at the orthostatic test | |||
SBP (supine) [mm Hg] | 139 ± 18 | 124 ± 12 | <0.01 |
DBP (supine) [mm Hg] | 83 ± 8 | 76 ± 8 | <0.01 |
SBP (orthostatism 1′) [mm Hg] | 111 ± 24 | 120 ± 15 | 0.02 |
DBP (orthostatism 1′) [mm Hg] | 71 ± 13 | 77 ± 9 | <0.01 |
SBP (orthostatism 3′) [mm Hg] | 110 ± 20 | 120 ± 14 | <0.01 |
DBP (orthostatism 3′) [mm Hg] | 71 ± 11 | 77 ± 8 | <0.01 |
Heart rate (supine) [b/min] | 73 ± 10 | 77 ± 12 | 0.09 |
Heart rate (orthostatism) [b/min] | 82 ± 12 | 87 ± 14 | 0.06 |
