Fig. 3

Changes in sitting blood pressure (BP) over time during treatment with esaxerenone. Sitting SBP (a), change from the baseline in SBP (b), sitting DBP (c) and change from the baseline in DBP (d). Data are means and 95% confidence intervals. *p < 0.05, paired t-test for changes from baseline (post hoc analysis). Dosage escalations occurred at weeks 4, 6, and 8. Full analysis set, n = 51. DBP diastolic BP, SBP systolic BP