Table 1 Baseline characteristics categorized according to the presence or absence of hyperuricemia
Variables | Normouricemia | Hyperuricemia | P value |
|---|---|---|---|
Men, n | 3461 | 786 | |
Range of uric acid, mg/dl | 0.7–7.0 | 2.7–10.3 | |
Medical treatment for hyperuricemia or gout, n | – | 159 | |
Age, years | 54.3 (9.9) | 52.5 (9.6) | <0.001 |
Systolic blood pressure, mmHg | 114.5 (11.8) | 116.7 (11.1) | <0.001 |
Diastolic blood pressure, mmHg | 71.8 (9.1) | 74.2 (8.5) | <0.001 |
eGFR <60 ml/min/1.73 m2, (%) | 7.5 | 18.7 | <0.001 |
Diabetes, (%) | 8.1 | 5.7 | 0.023 |
Dyslipidemia, (%) | 43.3 | 56.6 | <0.001 |
Overweight, (%) | 21.1 | 31.8 | <0.001 |
Alcohol consumption, (%) 0, 1–139, 140–274, ≥275 g/week | 28.7, 36.3, 24.2, 10.7 | 21.4, 33.2, 28.1, 17.3 | <0.001 |
Smoking status, (%) never, current, quit | 25.6, 35.4, 39.0 | 23.5, 30.9, 45.6 | 0.003 |
Physical Activity, (%) 0, 1–59, ≥60 min/week | 40.0, 32.3, 27.7 | 40.0, 32.6, 27.5 | 0.988 |
Family history of hypertension, (%) | 26.1 | 27.6 | 0.374 |
Women, n | 3414 | 187 | |
Range of uric acid, mg/dl | 0.5–5.9 | 4.4–10.8 | |
Medical treatment for hyperuricemia or gout, n | – | 3 | |
Age, years | 54.8 (9.2) | 56.8 (9.2) | 0.012 |
Systolic blood pressure, mmHg | 110.1 (12.9) | 113.5 (12.3) | <0.001 |
Diastolic blood pressure, mmHg | 68.2 (9.5) | 70.8 (9.3) | <0.001 |
eGFR < 60 ml/min/1.73 m2, (%) | 10.0 | 35.3 | <0.001 |
Diabetes, (%) | 2.7 | 4.8 | 0.088 |
Dyslipidemia, (%) | 36.1 | 52.9 | <0.001 |
Overweight, (%) | 11.9 | 30.0 | <0.001 |
Alcohol consumption, (%) 0, 1–69, ≥70 g/week | 70.9, 21.8, 7.3 | 69.5, 18.2, 12.3 | 0.031 |
Smoking status, (%) never, current, quit | 88.3, 6.1, 5.6 | 84.5, 4.3, 11.2 | 0.005 |
Physical activity, (%) 0, 1–59, ≥60 min/week | 40.1, 32.1, 27.8 | 44.9, 26.2, 28.9 | 0.223 |
Family history of hypertension, (%) | 36.3 | 40.1 | 0.295 |
