Fig. 5 | Hypertension Research

Fig. 5

From: Effects of an SGLT2 inhibitor on the salt sensitivity of blood pressure and sympathetic nerve activity in a nondiabetic rat model of chronic kidney disease

Fig. 5The alternative text for this image may have been generated using AI.

Impact of luseogliflozin treatment on locomotor activity (LA) and circadian rhythm. a Average 24-h LA during feeding with a NSD (0.3% NaCl) or a HSD (8% NaCl) and after switching back to a NSD in adenine-induced CKD rats with or without luseogliflozin treatment. *P < 0.05, **P < 0.01, ***P < 0.001 vs. vehicle group. Average 12-h LA in the inactive and active periods (b) during feeding with a NSD, (c) after 5 days of a HSD, and (d) 2 days after switching to a NSD. *P < 0.05, **P < 0.01, ***P < 0.001 vs. the inactive period of the respective group; #P < 0.05, ##P < 0.01, ###P < 0.001 vs. the active period of the vehicle group

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