Table 2 Clinical characteristics of the subjects on the basis of cutoff value of baPWV in patients with blood pressure <130/80 mmHg

From: Increased arterial stiffness and cardiovascular risk prediction in controlled hypertensive patients with coronary artery disease: post hoc analysis of FMD-J (Flow-mediated Dilation Japan) Study A

 

Low baPWV (<1731 cm/s)

High baPWV (≥1731 cm/s)

 

Variables

(n = 148)

(n = 53)

P value

Age, year

62.6 ± 9.4

68.8 ± 5.7

<0.001

Men, n (%)

128 (86.5)

46 (86.8)

0.96

Body mass index, kg/m2

24.7 ± 3.6

23.9 ± 2.7

0.15

Systolic blood pressure, mmHg

115.5 ± 9.1

118.8 ± 7.3

0.02

Diastolic blood pressure, mmHg

68.1 ± 7.1

66.6 ± 7.7

0.19

Heart rate, bpm

64.0 ± 11.1

68.2 ± 11.4

0.02

Total cholesterol, mmol/L

4.37 ± 0.77

4.43 ± 1.00

0.60

Triglycerides, mmol/L

1.64 ± 1.29

1.58 ± 0.95

0.73

HDL cholesterol, mmol/L

1.29 ± 0.35

1.23 ± 0.30

0.29

LDL cholesterol, mmol/L

2.35 ± 0.67

2.51 ± 0.96

0.19

Glucose, mmol/L

6.39 ± 2.24

7.14 ± 2.31

0.04

HbA1c, %

6.2 ± 0.8

6.7 ± 1.1

0.01

Creatinine, μmol/L

75.1 ± 23.9

79.6 ± 18.6

0.24

Smoker, n (%)

14 (9.8)

7 (13.2)

0.49

Complications, n (%)

  Dyslipidemia

143 (96.6)

48 (90.6)

0.08

  Diabetes mellitus

45 (30.4)

25 (47.2)

0.03

  Prior myocardial infarction

81 (54.7)

30 (56.6)

0.03

  Prior coronary intervention

133 (89.9)

47 (88.7)

0.81

Medication use, n (%)

Antiplatelet drugs

144 (97.3)

51 (96.2)

0.69

 ARBs/ACEIs

109 (73.7)

41 (77.4)

0.59

 β-blockers

83 (56.1)

27 (50.9)

0.52

 Calcium channel blockers

54 (36.5)

24 (45.3)

0.26

 Diuretics

18 (12.2)

10 (18.9)

0.23

 Antidiabetic drugs

36 (24.3)

21 (39.6)

0.04

 Statins

132 (89.2)

38 (71.7)

0.003

Left ventricular ejection fraction, %

60.4 ± 11.3

61.5 ± 8.8

0.53

Vessel diseased, n (%)

  1

86 (58.1)

26 (49.1)

0.41

  2

39 (26.4)

19 (35.9)

 

  3

23 (15.5)

8 (15.1)

 

LMT disease, n (%)

5 (3.4)

0 (0)

0.18

LAD disease, n (%)

96 (64.9)

37 (69.8)

0.51

LCX disease, n (%)

32 (21.6)

17 (32.1)

0.13

RCA disease, n (%)

48 (32.4)

21 (39.6)

0.34

BNP, pg/mL

32.8 ± 36.0

39.7 ± 57.8

0.32

baPWV, cm/s

1450 ± 153

1943 ± 209

NA

  1. All the results are presented as mean ± SD
  2. HDL high-density lipoprotein, LDL low-density lipoprotein, ARB angiotensin receptor blocker, ACEI angiotensin-converting enzyme inhibitor, LMT left main trunk, LAD left anterior descending coronary artery, LCX left circumflex coronary artery, RCA right coronary artery, BNP brain natriuretic peptide, baPWV brachial-ankle pulse wave velocity, NA not applicable
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