Table 3 Association between baPWV and cardiovascular events during follow-up in patients with blood pressure <130/80 mmHg

From: Increased arterial stiffness and cardiovascular risk prediction in controlled hypertensive patients with coronary artery disease: post hoc analysis of FMD-J (Flow-mediated Dilation Japan) Study A

Variable

Hazard ratio (95% confidence interval); P value

baPWV (cm/s)

Unadjusted

Model 1a

Model 2b

Model 3c

Model 4d

baPWV < 1731

1 (reference)

1 (reference)

1 (reference)

1 (reference)

1 (reference)

baPWV ≥ 1731

2.94 (1.26–6.86); 0.01

3.00 (1.22–7.46); 0.02

2.67 (1.03–6.91); 0.04

3.02 (1.16–7.99); 0.02

2.69 (1.02–7.34); 0.04

  1. baPWV brachial–ankle pulse wave velocity
  2. aModel 1: adjusted for age and sex
  3. bModel 2: adjusted for age, sex, body mass index, systolic blood pressure, dyslipidemia, diabetes mellitus, and current smoking
  4. cIn Model 3, backward stepwise Cox proportional hazard regression analysis was performed with potentially confounding variables that differed between the groups based on baPWV cutoff value using inclusion criterion of P < 0.10. Variables with P < 0.25 (heart rate, glucose, antidiabetic drugs, and prior myocardial infarction) were retained in the final model with age and sex forced into the model
  5. dModel 4: adjusted for age, sex, body mass index, systolic blood pressure, dyslipidemia, diabetes mellitus, current smoking, number of diseased vessels, and left anterior descending coronary artery disease
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