Table 4 Laboratory parameters of hypertensive and non- hypertensive COVID-19 patients without other comorbidities

From: COVID-19 patients with hypertension have more severe disease: a multicenter retrospective observational study

Ā 

Normal range

Total (n = 225)

Nonhypertension (n = 160)

Hypertension (n = 65)

P value

Laboratory indices

WBC, Ɨ109/L

4.00–10.00

5.23 (3.90–7.67)

3.25 (2.34–9.51)

7.36 (4.86–9.73)

0.002

NC, Ɨ109/L

1.80–6.30

3.79 (2.59–6.18)

2.52 (1.62–8.63)

7.92 (3.43–8.86)

0.003

LC, Ɨ109/L

1.10–3.20

0.86 (0.59–1.19)

0.54 (0.48–0.62)

0.65 (0.40–0.85)

0.624

NLR

<5.87

4.63 (2.48–8.44)

5.15 (3.03–13.81)

14.96 (3.6–20.23)

0.042

SaO2, %

>95.0

96.0 (91.3–98.0)

95.4 (91.5–98.1)

94.8 (82.0–96.7)

0.001

TB, μmol/L

5.10–19.00

11.15 (8.48–15.10)

10.55 (8.78–13.00)

10.60 (9.75–13.40)

0.375

ALT, U/L

<40.0

27.4 (17.9–48.0)

20.0 (9.50–26.0)

46.5 (22.3–204.8)

0.001

AST, U/L

<40.0

32.0 (23.0–47.3)

36.5 (32.3–40.8)

33.5 (25.8–94.8)

0.060

Albumin, g/L

34.0–54.0

34.2 (30.5–38.1)

28.3 (27.2–32.0)

30.4 (29.0–32.3)

0.008

Globulin, g/L

20.0–35.0

30.5 (26.1–34.6)

29.4 (25.0–32.2)

29.8 (26.6–32.9)

0.129

LDH, U/L

109–245

286 (207–409)

302 (250–407)

316 (245–412)

0.038

Creatinine, μmol/L

50.00–120.00

68.00 (55.50–81.35)

76.35 (56.43–87.43)

64.50 (54.18–110.15)

0.090

ESR, mm/h

<15.0

46.2 (25.3–62.5)

42.0 (19.3–58.8)

49.0 (25.0–77.8)

0.160

CRP, mg/L

<8.0

13.2 (2.9–61.7)

44.4 (39.8–146.1)

31.4 (16.9–96.0)

0.011

Serum ferritin, ng/mL

21.80–275.0

790.52 (401.97–1324.91)

1082.60 (617.30–1339.50)

762.72 (533.98–1178.14)

0.288

IL-6, pg/mL

0.10–2.90

9.36 (6.52–13.80)

9.10 (5.44–34.27)

9.62 (6.51–13.47)

0.194

BNP, pg/mL

0.0–100.0

62.9 (26.6–115.8)

73.0 (32.4–253.5)

73.2 (30.0–127.7)

0.877

D-dimer, ug/mL

<0.50

0.67 (0.42–1.79)

0.74 (0.48–2.06)

1.09 (0.56–3.48)

0.013

FIB, g/L

2.00–4.00

3.60 (2.86–4.80)

4.35 (3.53–5.55)

4.50 (3.83–6.25)

0.036

PT, s

11.0–16.0

11.3 (10.6–12.2)

11.5 (10.1–12.5)

11.5 (10.0–12.5)

0.127

APTT, s

27.0–45.0

28.2 (25.0–32.5)

30.8 (26.5–33.6)

22.3 (19.3–32.2)

0.004

  1. WBC white blood cell count, NC neutrophil count, LC lymphocyte count, NLR neutrophil-to-lymphocyte ratio, SaO2 oxyhemoglobin saturation, TB total bilirubin, ALT alanine aminotransferase, AST aspartate aminotransferase, LDH lactate dehydrogenase, ESR erythrocyte sedimentation rate, CRP c-reactive protein, IL-6 interleukin-6, BNP b-type natriuretic peptide, FIB fibrinogen, PT prothrombin time, APTT activated partial thromboplastin time