Fig. 3
From: Cell seeding accelerates the vascularization of tissue engineering constructs in hypertensive mice
Time course of functional microvascular densities. Quantitative assessment of the functional microvascular density of newly formed microvessels, given in cm/cm2, of collagen-coated (Coll) PLGA scaffolds (hypertensive mice (BPH/2J): light gray bars; controls (BPN/3J): dark gray bars), PLGA scaffolds additionally seeded with OLCs (Coll + OLCs) (hypertensive mice: light blue bars; controls: dark blue bars) or bmMSCs (Coll + bmMSCs) (hypertensive mice: light green bars; controls: dark green bars) immediately (day 0) as well as 3, 6, 10, and 14 days after implantation into the dorsal skinfold chamber (each group, n = 8). Data are presented as means ± SEMs. *p < 0.05 versus controls with collagen-coated scaffolds and all hypertensive groups; °p < 0.05 versus hypertensive mice with collagen-coated scaffolds; +p < 0.05 versus the same group on the previous day; #p < 0.05 versus hypertensive mice with collagen-coated scaffolds
