Fig. 4
From: Cell seeding accelerates the vascularization of tissue engineering constructs in hypertensive mice

Histological sections of paraffin-embedded specimens 14 days after implantation into the skinfold chamber. HE staining of collagen-coated PLGA scaffolds (controls: a and b; hypertensive mice: g and h) and PLGA scaffolds additionally seeded with OLCs (controls: c and d; hypertensive mice: i and j) or with bmMSCs (controls: e and f; hypertensive mice: k and l). Low-magnification pictures (left column: a, c, e, g, i, and k) provide an overview of the gross appearance of the scaffolds. After 14 days, the scaffold strands (asterisks) were embedded in the vascularized granulation tissue. The differences in microvascular densities are clarified by higher magnification pictures (right column: b, d, f, h, j, and l). Arrows denote the vascular structures