Fig. 4

Activities of mitochondrial respiratory chain complexes and citrate synthase (CS) in the right ventricle (RV) and brain of rats with monocrotaline (MCT)-induced pulmonary arterial hypertension (PAH). A Complex II activity in the RV; B complex II–III activity in the RV; C complex IV activity in the RV; D CS activity in the RV; E complex II activity in the brain; F complex II–III activity in the brain; G complex IV activity in the brain; H CS activity in the brain. Data are expressed as the mean ± standard deviation (n = 6). *P < 0.05 vs control; **P < 0.01 vs control