Fig. 5 | Hypertension Research

Fig. 5

From: Rivaroxaban attenuates cardiac hypertrophy by inhibiting protease-activated receptor-2 signaling in renin-overexpressing hypertensive mice

Fig. 5

Effects of the PAR-2 antagonist FSLLRY on cardiac hypertrophy and heart weight in Ren-Tg mice. A LV wall thickness (interventricular septum + posterior wall thickness) in Ren-Tg mice treated with or without FSLLRY, evaluated by echocardiography (n = 3–4). Comparisons were made by unpaired Student’s t test. B Heart weight:body weight ratio in Ren-Tg mice after 4 weeks of treatment with or without FSLLRY (n = 3–5). Comparisons were made by unpaired Student’s t test. Ren-Tg indicates renin-overexpressing hypertensive transgenic, PAR-2 protease-activated receptor-2, LV left ventricular

Back to article page