Table 1 Systolic blood pressure and pulse rate in WT and Ren-Tg mice after 4 weeks of treatment

From: Rivaroxaban attenuates cardiac hypertrophy by inhibiting protease-activated receptor-2 signaling in renin-overexpressing hypertensive mice

 

WT mice

Ren-Tg mice

Riv

−

+

−

+

SBP (mmHg)

101 ± 4

99 ± 3

130 ± 3*

119 ± 9†

Pulse rate (bpm)

600 ± 41

648 ± 45

683 ± 21**

696 ± 31

  1. n = 6 in each group
  2. WT wild type, Ren-Tg renin-overexpressing hypertensive, Riv rivaroxaban, SBP systolic blood pressure
  3. *p < 0.0001 vs. WT without Riv, **p = 0.003 vs. WT without Riv, †p  = 0.01 vs. Ren-Tg without Riv
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