Table 1 Baseline characteristics for SPYRAL HTN ON-MED patients prescribed ≥ 3 antihypertensive drugs at 36 months
Patient demographics | RDN | CONTROL | P VALUE |
|---|---|---|---|
Age (years) | 55.1 ± 8.8 (23) | 51.0 ± 10.2 (23) | 0.1456 |
Female | 4.3% (1/23) | 17.4% (4/23) | 0.3463 |
Male | 95.7% (22/23) | 82.6% (19/23) | 0.3463 |
Race | |||
White | 39.1% (9/23) | 34.8% (8/23) | 1.0000 |
Black or African American | 8.7% (2/23) | 17.4% (4/23) | 0.6652 |
BMI (kg/m2) | 32.3 ± 5.4 (23) | 33.8 ± 4.5 (23) | 0.3258 |
Estimated glomerular filtration rate (ml/min/1·73 m²) | 80.1 ± 15.1 (23) | 81.0 ± 19.1 (23) | 0.8605 |
Type 2 Diabetes | 8.7% (2/23) | 30.4% (7/23) | 0.1346 |
Current Smoker | 21.7% (5/23) | 26.1% (6/23) | 1.0000 |
History of Sleep Apnea | 17.4% (4/23) | 39.1% (9/23) | 0.1894 |
History of Coronary Artery Disease | 0.0% (0/23) | 4.3% (1/23) | 1.0000 |
History of Peripheral Artery Disease | 0.0% (0/23) | 0.0% (0/23) | NA |
History of Stroke | 0.0% (0/23) | 0.0% (0/23) | NA |
Blood Pressure | |||
Office systolic blood pressure | 166.0 ± 5.9 (23) | 162.1 ± 7.5 (23) | 0.0595 |
Office diastolic blood pressure | 99.6 ± 7.1 (23) | 102.0 ± 7.4 (23) | 0.2831 |
Mean 24 h systolic blood pressure | 151.8 ± 6.1 (23) | 152.4 ± 6.9 (22) | 0.7512 |
Mean 24 h diastolic blood pressure | 96.7 ± 7.4 (23) | 98.9 ± 7.1 (22) | 0.3296 |
Morning systolic blood pressure | 156.6 ± 13.7 (23) | 155.0 ± 16.9 (22) | 0.7342 |
Morning diastolic blood pressure | 102.4 ± 10.9 (23) | 102.0 ± 14.7 (22) | 0.9082 |
Nighttime systolic blood pressure | 141.7 ± 13.8 (23) | 142.8 ± 9.2 (22) | 0.7457 |
Nighttime diastolic blood pressure | 89.1 ± 14.1 (23) | 91.4 ± 9.4 (22) | 0.5368 |
