Table 1 Demographic, anthropometric, clinical characteristics and haemodynamic variables were extracted from 24 h ambulatory blood pressure monitoring patients without pharmacological treatment
From: Hemodynamic profiles of arterial hypertension with ambulatory blood pressure monitoring
Patients without pharmacological treatment n = 7473 | ||||||
|---|---|---|---|---|---|---|
Variables | Normotensive | IDH | ND-SDH | D-SDH | ISH | P value |
n = 1950 (26.1%) | n = 2109 (28.2%) | n = 2005 (26.8%) | n = 1207 (16.2%) | n = 202 (2.7%) | ||
Mean SD [p5, p95] | Mean SD [p5, p95] | Mean SD [p5, p95] | Mean SD [p5, p95] | Mean SD [p5, p95] | ||
Age (years) | 45.0 ± 14.2 [23.1, 68.7] | 44.7 ± 10.9 [27.3, 63.3] | 45.4 ± 10.8 [28.3, 63.1] | 50.3 ± 14.6 [24.7, 73.3] | 58.6 ± 19.7 [22.1, 85.3] | <0.001 |
Body mass index (kg/m2) | 26.1 ± 3.8 [20.2, 32.9] | 26.8 ± 3.7 [21.2, 33.5] | 27.9 ± 3.9 [22.0, 34.9] | 28.4 ± 4.4 [22.2, 36.4] | 27.1 ± 4.1 [21.3, 35.7] | <0.001 |
Body surface area (m2) | 1.81 ± 0.20 [1.50, 2.18] | 1.86 ± 0.20 [1.53, 2.20] | 1.92 ± 0.21 [1.57, 2.27] | 1.91 ± 0.23 [1.55, 2.28] | 1.80 ± 0.23 [1.46, 2.19] | <0.001 |
Heart rate (beats per min) | 72.8 ± 9.1 [57.8, 87.8] | 76.6 ± 8.6 [63.0, 90.7] | 77.2 ± 9.3 [62.2, 92.3] | 73.7 ± 9.2 [58.9, 88.6] | 70.8 ± 9.5 [55.7, 89.6] | <0.001 |
Systolic blood pressure (mmHg) | 117.1 ± 6.8 [104.7, 127.7] | 124.6 ± 3.7 [117.5, 129.5] | 136.6 ± 5.5 [130.4, 148.0] | 146.4 ± 9.5 [133.8, 163.2] | 135.8 ± 5.0 [130.3, 146.7] | <0.001 |
Diastolic blood pressure (mmHg) | 75.2 ± 3.9 [67.9, 79.6] | 84.0 ± 2.7 [80.3, 88.0] | 91.2 ± 5.4 [83.2, 101.6] | 90.9 ± 7.6 [81.2, 105.0] | 76.6 ± 3.3 [69.5, 79.8] | <0.001 |
Mean arterial pressure (mmHg) | 89.2 ± 4.2 [81.4, 94.6] | 97.5 ± 2.7 [93.3, 102.0] | 106.3 ± 5.3 [99.5, 116.8] | 109.4 ± 7.9 [99.0, 123.5] | 96.3 ± 2.7 [91.5, 100.2] | <0.001 |
Pulse pressure (mmHg) | 41.8 ± 5.8 [33.3, 51.6] | 40.6 ± 3.5 [34.6, 46.3] | 45.4 ± 3.0 [39.9, 49.5] | 55.5 ± 5.4 [50.3, 66.2] | 59.1 ± 6.2 [51.6, 72.8] | <0.001 |
Stroke volume/BSA (mL/m2) | 41.7 ± 2.2 [38.1, 45.2] | 40.9 ± 1.9 [37.6, 43.9] | 41.2 ± 2.3 [37.3, 44.6] | 42.5 ± 2.8 [37.7, 46.7] | 43.1 ± 3.2 [38.1, 47.9] | <0.001 |
Cardiac index (L/min/m2) | 3.01 ± 0.24 [2.57, 3.39] | 3.12 ± 0.22 [2.74, 3.45] | 3.16 ± 0.22 [2.75, 3.49] | 3.11 ± 0.22 [2.72, 3.45] | 3.03 ± 0.23 [2.64, 3.41] | <0.001 |
Total arterial compliance (mL/mmHg) | 1.01 ± 0.20 [0.68, 1.34] | 1.03 ± 0.18 [0.74, 1.33] | 0.95 ± 0.17 [0.67, 1.23] | 0.80 ± 0.18 [0.52, 1.10] | 0.72 ± 0.19 [0.42, 1.10] | <0.001 |
Total peripheral resistance (dyn*s/cm−5) | 1329 ± 183 [1045,1644] | 1365 ± 186 [1087,1686] | 1422 ± 205 [1123,1793] | 1499 ± 228 [1140,1906] | 1441 ± 227 [1056,1799] | <0.001 |
n | % | n | % | n | % | n | % | n | % | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Men | 856 | 44 | 1162 | 55 | 1302 | 65 | 697 | 58 | 79 | 39 | <0.001 | |
Level of physical activity | I | 1176 | 60 | 1329 | 63 | 1317 | 66 | 759 | 63 | 123 | 61 | 0.015 |
II | 448 | 23 | 449 | 21 | 410 | 20 | 248 | 21 | 45 | 22 | ||
III | 326 | 17 | 331 | 16 | 278 | 14 | 200 | 17 | 34 | 17 | ||
Frequent alcohol intake | 211 | 11 | 308 | 15 | 347 | 17 | 216 | 18 | 24 | 12 | <0.001 | |
Current smoking | 92 | 5 | 121 | 6 | 140 | 7 | 99 | 8 | 16 | 8 | 0.001 | |