Table 1 Characteristics of the study population at the baseline
Total n = 1186 | With HT&DL n = 553 | With HT n = 304 | With DL n = 178 | Without HT&DL n = 151 | |
|---|---|---|---|---|---|
Baseline | |||||
Male (%) | 567 (47.8) | 247 (44.7) | 174 (57.2) | 63 (35.4) | 83 (55.0) |
Age | |||||
70 yr (%) | 573 (48.3) | 235 (42.5) | 125 (41.1) | 117 (65.7) | 96 (63.6) |
80 yr (%) | 551 (46.5) | 286 (51.7) | 160 (52.6) | 54 (30.3) | 51 (33.8) |
90 yr (%) | 62 (5.2) | 32 (5.8) | 19 (6.3) | 7 (3.9) | 4 (2.6) |
SBP (mmHg) | 142.4 ± 19.2 | 149.2 ± 17.0 | 149.3 ± 16.3 | 125.8 ± 12.5 | 123.3 ± 12.9 |
DBP (mmHg) | 78.1 ± 10.7 | 80.1 ± 10.8 | 80.5 ± 10.5 | 73.2 ± 8.4 | 72.1 ± 9.0 |
HT (%) | 857 (72.3) | 553 (100.0) | 304 (100.0) | 0 (0) | 0 (0) |
Medication for HT (%) | 544 (45.9) | 361 (65.3) | 183 (60.2) | 0 (0) | 0 (0) |
LDL-C (mg dL-1) | 119.9 ± 29.8 | 123.1 ± 33.3 | 111.2 ± 20.4 | 134.1 ± 30.8 | 109.4 ± 21.1 |
LDL-C ≥ 140 (%) | 279 (23.5) | 192 (34.7) | 0 (0) | 87 (48.9) | 0 (0) |
HDL-C (mg dL-1) | 61.0 ± 15.9 | 57.4 ± 15.3 | 64.7 ± 14.6 | 60.9 ± 16.9 | 66.6 ± 15.9 |
HDL-C < 40 (%) | 84 (7.1) | 63 (11.4) | 0 (0) | 21 (11.8) | 0 (0) |
TG (mg dL-1) | 132.0 ± 73.6 | 163.2 ± 80.0 | 92.4 ± 30.5 | 144.8 ± 78.1 | 82.1 ± 27.1 |
TG ≥ 150 (%) | 345 (29.1) | 278 (50.3) | 0 (0) | 67 (37.6) | 0 (0) |
DL (%) | 731 (61.6) | 553 (100.0) | 0 (0) | 178 (100.0) | 0 (0) |
Medication for DL (%) | 295 (24.9) | 234 (42.3) | 0 (0) | 61 (34.3) | 0 (0) |
DM (%) | 122 (10.3) | 69 (2.5) | 27 (8.9) | 17 (9.6) | 9 (6.0) |
BMI (kg m-2) | 22.7 ± 3.3 | 23.3 ± 3.0 | 22.5 ± 3.9 | 22.1 ± 2.6 | 21.1 ± 2.8 |
MoCA-J total score (0–30) | 22.9 ± 3.5 | 22.8 ± 3.4 | 22.5 ± 3.7 | 23.5 ± 3.6 | 23.4 ± 3.1 |
Smoking history (%) | 426 (35.9) | 198 (35.8) | 116 (38.2) | 58 (32.6) | 54 (35.8) |
Drinking history (%) | 493 (41.6) | 212 (38.3) | 162 (53.3) | 49 (27.5) | 70 (46.4) |
Follow-up | |||||
SBP (mmHg) | 138.6 ± 18.3 | 141.5 ± 17.6 | 143.5 ± 7.9 | 130.3 ± 16.2 | 128.2 ± 17.0 |
DBP (mmHg) | 75.5 ± 11.1 | 76.1 ± 11.1 | 76.7 ± 11.6 | 74.0 ± 10.3 | 72.8 ± 10.2 |
HT (%) | 830 (70.0) | 461 (83.4) | 257 (84.5) | 67 (37.6) | 45 (29.8) |
Medication for HT (%) | 559 (47.1) | 345 (62.4) | 177 (58.2) | 21 (11.8) | 16 (10.6) |
LDL-C (mg dL-1) | 114.9 ± 29.9 | 116.2 ± 32.5 | 110.4 ± 24.1 | 124.5 ± 32.1 | 107.7 ± 24.1 |
LDL-C ≥ 140 (%) | 210 (17.7) | 112 (20.3) | 29 (9.5) | 57 (32.0) | 12 (7.9) |
HDL-C (mg dL-1) | 59.7 ± 15.3 | 57.2 ± 15.0 | 62.7 ± 14.9 | 59.6 ± 15.7 | 63.0 ± 15.2 |
HDL-C < 40 (%) | 85 (7.2) | 57 (10.3) | 9 (3.0) | 15 (8.4) | 4 (2.6) |
TG (mg dL-1) | 133.9 ± 76.7 | 155.3 ± 82.1 | 107.3 ± 62.0 | 141.7 ± 74.3 | 100.7 ± 56.3 |
TG ≥ 150 (%) | 364 (30.7) | 235 (42.5) | 52 (17.1) | 57 (32.0) | 20 (13.2) |
DL (%) | 720 (60.7) | 438 (79.2) | 104 (34.2) | 136 (76.4) | 42 (27.8) |
Medication for DL (%) | 335 (28.2) | 238 (43.0) | 26 (8.6) | 61 (34.3) | 10 (6.6) |
Combinated HT (%) | 530 (0.4) | 370 (0.7) | 91 (0.3) | 26 (0.2) | 19 (0.1) |
DM (%) | 161 (13.6) | 91 (16.5) | 35 (11.5) | 19 (10.7) | 16 (10.6) |
BMI (kg m-2) | 22.7 ± 3.1 | 23.3 ± 3.2 | 22.4 ± 3.2 | 22.3 ± 2.7 | 21.2 ± 2.8 |
MoCA-J total score (0–30) | 23.0 ± 3.9 | 23.1 ± 3.7 | 22.4 ± 4.3 | 23.6 ± 3.9 | 23.4 ± 3.4 |
Smoking history (%) | 437 (36.8) | 201 (36.3) | 118 (38.8) | 60 (33.7) | 58 (38.4) |
Drinking history (%) | 486 (41.0) | 213 (38.5) | 152 (50.0) | 52 (29.2) | 69 (45.7) |
Cerebro & Cardio vascular disease (%) | 33 (2.8) | 23 (4.2) | 4 (1.3) | 4 (2.2) | 2 (1.3) |
