Table 3 Adjusted blood pressure values and the odds ratios for hypertension according to 3%ODI levels, stratified analysis by obesity status

From: Sleep-related breathing disorder in a Japanese occupational population and its association with hypertension—stratified analysis by obesity status

 

No. of subjects

Model 1

Model 2

Systolic blood pressure

 BMI < 25 kg/m2

   0 ≤ 3%ODI < 5

1417

117.6 ± 1.9

117.8 ± 5.2

   5 ≤ 3%ODI < 15

358

119.2 ± 2.0

118.8 ± 5.2

   15 ≤ 3%ODI

37

121.5 ± 2.7

120.3 ± 5.6

  

p for trend < 0.0001

p for trend < 0.0001

 BMI ≥ 25 kg/m2

   0 ≤ 3%ODI < 5

387

123.3 ± 3.3

123.4 ± 6.8

   5 ≤ 3%ODI < 15

269

124.9 ± 3.4

124.9 ± 6.8

   15 ≤ 3%ODI

64

124.9 ± 3.7

124.3 ± 7.0

  

p for trend<0.0001

p for trend < 0.0001

Diastolic blood pressure

 BMI < 25 kg/m2

   0 ≤ 3%ODI < 5

1417

75.1 ± 1.4

75.2 ± 4.0

   5 ≤ 3%ODI < 15

358

76.3 ± 1.5

76.1 ± 4.0

   15 ≤ 3%ODI

37

77.5 ± 2.0

76.8 ± 4.3

  

p for trend < 0.0001

p for trend < 0.0001

 BMI ≥ 25 kg/m2

   0 ≤ 3%ODI < 5

387

80.0 ± 2.5

80.2 ± 5.3

   5 ≤ 3%ODI < 15

269

81.2 ± 2.6

81.0 ± 5.3

   15 ≤ 3%ODI

64

82.0 ± 2.8

81.5 ± 5.4

  

p for trend < 0.0001

p for trend < 0.0001

Odds ratio for hypertension

 BMI < 25 kg/m2

   0 ≤ 3%ODI < 5

1417

1.00 (Reference)

1.00 (Reference)

   5 ≤ 3%ODI < 15

358

1.56 (1.15–2.12)

1.47 (1.07–2.02)

   15 ≤ 3%ODI

37

2.95 (1.426–6.11)

2.40 (1.13–5.10)

  

p for trend < 0.001

p for trend = 0.008

 BMI ≥ 25 kg/m2

   0 ≤ 3%ODI < 5

387

1.00 (Reference)

1.00 (Reference)

   5 ≤ 3%ODI < 15

269

0.96 (0.67–1.36)

0.95 (0.66–1.37)

   15 ≤ 3%ODI

64

1.05 (0.58–1.09)

1.01 (0.54–1.88)

  

p for trend = 0.94

p for trend = 0.95

  

p for interaction = 0.015

p for interaction = 0.03

  1. Data are presented as the adjusted mean values (standard error) or odds ratio (95% confidence interval)
  2. Model 1: Adjusted for age and sex
  3. Model 2: Adjusted for age, sex, current alcohol drinking, current smoking, regular exercise, heart rate, HbA1c, use of glucose-lowering agents, serum LDL cholesterol, serum HDL cholesterol, and eGFR
  4. 3%ODI 3% oxygen desaturation index, BMI body mass index