Fig. 2 | Hypertension Research

Fig. 2

From: G protein-coupled receptor kinases in hypertension: physiology, pathogenesis, and therapeutic targets

Fig. 2

Regulation of blood pressure by GRKs. GRKs exert their functions in organs, including kidney, artery, and heart, by regulating the expression or phosphorylation of various GPCRs to modulate blood pressure. Pink color: various substrates regulated by GRKs. α-1DAR α-1D adrenergic receptor, adipoR1 adiponectin receptor 1, Ang II angiotensin II, AT1R angiotensin II type 1 receptor, AT2R angiotensin II type 2 receptor, β-AR β-adrenergic receptor, D1R dopamine D1 receptor, D3R dopamine D3 receptor, ETBR endothelin receptor type B, GRK G protein-coupled receptor kinase, P2Y2R P2Y2 receptor

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