Table 1 Characteristics of the study population

From: Urinary metabolomics signature of animal and plant protein intake and its association with 24-h blood pressure: the African-PREDICT study

 

Total group N = 1008

Low-risk group N = 102 (Low animal & high plant protein intake)

High-risk group N = 90 (Low plant and high animal protein intake)

Mean difference (SE)

p value

Men, N (%)

506 (50.2)

50 (49.0)

48 (53.3)

 

0.55

White ethnicity, N (%)

503 (49.9)

55 (53.9)

48 (53.3)

 

0.94

Socioeconomic status

    

0.049

  Low

402 (39.9)

46 (45.5)

27 (30.0)

  

  Middle

303 (30.1)

29 (28.7)

27 (30.0)

  

  High

302 (30.0)

26 (25.7)

36 (40.0)

  

  Age (years)

24.5 ± 3.12

24.1 ± 3.23

24.7 ± 3.23

 

0.15

Anthropometric profile

  Waist circumference (cm)

78.5 (16.7)

75.1 (15.0)

83.9 (17.3)

6.73 (1.76)

<0.001

  Body Mass Index (kg/m2)

24.2 (6.72)

22.3 (6.48)

25.9 (6.32)

2.90 (0.81)

<0.001

Physical activity

  TEE (kCal/day/kg)

32.6 ± 4.60

33.3 ± 4.81

32.3 ± 4.58

−1.08 (0.77)

0.16

Blood pressure profile

  24-h SBP (mmHg)

117 ± 9.42

114 ± 9.26

117 ± 8.45

3.32 (1.30)

0.011

  24-h DBP (mmHg)

68 ± 5.77

67 ± 5.25

68 ± 5.62

1.17 (0.79)

0.14

Urinary profile

  Salt intake (g/day)

8.12 (5.77)

8.53 (6.21)

7.88 (6.23)

−0.35 (0.75)

0.77

  Sodium excretion (mmol/day)

137.6 (97.8)

144.6 (105)

133.6 (105)

−5.90 (12.8)

0.77

  Potassium excretion (mmol/day)

44.1 (37.8)

40.4 (26.4)

51.1 (43.3)

11.5 (4.45)

0.039

  Na+/K+ ratio

3.21 (2.23)

3.36 (2.64)

2.79 (2.06)

−0.67 (0.29)

0.017

Biochemical profile

  Total cholesterol (mmol/L)

3.66 ± 1.16

3.36 ± 1.13

3.90 ± 1.18

0.54 (0.17)

0.002

  HDL-C (mmol/L)

1.11 ± 0.40

1.03 ± 0.36

1.13 ± 0.45

0.10 (0.06)

0.098

  LDL-C (mmol/L)

2.39 ± 0.93

2.16 ± 0.84

2.55 ± 0.90

0.39 (0.13)

0.003

  HbA1c (%)

5.31 ± 0.32

5.32 ± 0.29

5.29 ± 0.34

−0.03 (0.05)

0.50

  GGT (U/L)

17.1 (16.8)

15.1 (14.0)

17.8 (17.1)

4.94 (2.20)

0.007

  CRP (mg/L)

0.83 (2.17)

0.54 (1.73)

1.12 (2.22)

0.45 (0.49)

0.007

24-h Dietary recall

  Energy intake (KJ)

7702 (3590)

8222 (3307)

7516 (2384)

−461.5 (326)

0.13

  Total protein intake (g)

69.5 (40.0)

56.7 (24.1)

88.2 (35.2)

34.9 (3.26)

<0.001

  Plant protein intake (g)

19.0 (12.2)

28.9 (10.5)

11.8 (4.49)

−20.4 (1.35)

<0.001

  Animal protein intake (g)

41.2 (36.2)

19.8 (15.2)

74.2 (34.2)

57.4 (2.98)

<0.001

  Potassium intake (mg)

1851 (1175)

1809 (921)

2116 (1121)

205 (111)

0.031

  Fibre intake (g)

13.0 (9.46)

19.1 (11.0)

8.92 (4.77)

−11.3 (1.04)

<0.001

  Total fat (g)

66.7 (46.0)

65.6 (47.8)

80.2 (50.9)

14.0 (5.06)

0.007

  Saturated fat (g)

20.9 (16.5)

20.3 (14.1)

26.7 (21.1)

8.37 (1.75)

<0.001

  Mono-unsaturated fat (g)

22.8 (17.7)

20.9 (17.2)

27.9 (19.4)

6.56 (1.89)

0.001

  Polyunsaturated fat (g)

14.4 (12.9)

15.3 (16.1)

14.0 (10.8)

−1.84 (1.68)

0.51

  1. Normally distributed data presented as arithmetic mean ± standard deviation. Compared using independent T-tests
  2. Skewed data presented as median (IQR). Compared using Mann–Whitney U tests
  3. Mean difference (SE) was determined from independent t-tests
  4. CRP C-reactive protein, DBP Diastolic blood pressure, GGT Gamma-glutamyl transferase, HDL-C High-density lipoprotein cholesterol, LDL-C Low-density lipoprotein cholesterol, SBP Systolic blood pressure, TEE Total energy expenditure