Abstract
Asian countries are rapidly embracing digital technologies amid rising hypertension prevalence and aging populations. While digital tools like mobile apps, telehealth reminders, and AI-driven interventions have shown global success in managing hypertension, their adoption in Asia remains limited due to cultural dietary habits, disparities in digital literacy and access, and fragmented healthcare infrastructure present unique barriers to equitable implementation. This mini review examines key challenges and opportunities in applying digital health interventions to improve hypertension adherence in the region. We identify five critical barriers: (1) difficulty in monitoring dietary sodium intake due to limited practical tools and regional dietary diversity, (2) low digital engagement among older adults, who are disproportionately affected by hypertension, (3) lack of interoperability between digital platforms and healthcare systems, (4) a fragmented regulatory landscape that hinders consistent oversight and adoption, and (5) challenges in sustaining long-term user engagement. Achieving meaningful impact will require cross-sector collaboration to standardize data protocols, improve regulatory alignment, ensure affordability, and support user-centered design. As evidence for outcome-based effectiveness grows, digital tools can be integrated into national strategies to reduce cardiovascular disease risk and healthcare costs. Tailoring these technologies to the needs of Asian populations is essential to achieving equitable, sustainable hypertension care and fostering long-term public health resilience across the region.

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MS has been partially supported by research funding from Polybio, Pfizer, and Novartis through Yale University; he has also received lecture honoraria from Boehringer Ingelheim. YL received support from the National Heart, Lung, and Blood Institute of the National Institutes of Health (under awards R01HL69954 and R01HL169171), the Patient-Centered Outcomes Research Institute (under award HM-2022C2-28354), Sentara Research Foundation, and Novartis through Yale University.
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Yang, H., Sawano, M. & Lu, Y. Improving adherence in hypertension management: digital tools, barriers, and innovations across Asia. Hypertens Res 48, 2079–2082 (2025). https://doi.org/10.1038/s41440-025-02227-7
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DOI: https://doi.org/10.1038/s41440-025-02227-7


