Fig. 3 | Hypertension Research

Fig. 3

From: Dark-phase melatonin administration does not reduce blood pressure but induces changes in parameters related to the control of the cardiovascular system in spontaneously hypertensive rats

Fig. 3

Time- and frequency domain parameters in rats with nocturnal melatonin administration at three concentrations (Mel2, n = 7; Mel10, n = 5 and Mel45, n = 8) and in the placebo group (n = 9). Graphs contain the results of two-way ANOVA. C control week, M1, M2 and M3 first, second and third week with melatonin administration, LF low frequency, HF high frequency, sBRS spontaneous baroreflex sensitivity, NN9 number of pairs of successive normal-to-normal intervals that differ by more than 9 ms, pNN9 proportion of NN9 intervals, SDNN the standard deviation of normal-to-normal intervals, RMSSD the root mean square of successive differences between normal heartbeats. Data are visualised as individual datapoints and arithmetic mean ± the standard error of the mean

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