Table 4 Multivariable analysis of relationships of FMD and NID with variables
From: Relationship of TMAO levels with vascular function in patients with hypertension
Variables | FMD | NID | ||||||
|---|---|---|---|---|---|---|---|---|
β | VIF | t value | P value | β | VIF | t value | P value | |
Age, year | −0.22 | 1.83 | −2.68 | <0.01 | −0.28 | 1.82 | −3.36 | <0.01 |
Body mass index, kg/m2 | −0.09 | 1.27 | −1.30 | 0.20 | −0.16 | 1.38 | −2.27 | 0.02 |
Heart rate, bpm | 0.07 | 1.21 | 1.00 | 0.32 | 0.04 | 1.21 | 0.61 | 0.54 |
Systolic blood pressure, mmHg | 0.19 | 1.30 | 2.79 | <0.01 | 0.03 | 1.31 | 0.42 | 0.67 |
Triglycerides, mg/dL | −0.03 | 1.40 | −0.41 | 0.68 | −0.04 | 1.38 | −0.60 | 0.55 |
HDL-C, mg/dL | <0.01 | 1.66 | 0.00 | 1.00 | 0.08 | 1.66 | 1.08 | 0.28 |
Total cholesterol, mg/dL | −0.03 | 1.46 | −0.03 | 0.70 | 0.03 | 1.47 | 0.41 | 0.69 |
eGFR, mL/min/1.73m2 | −0.02 | 1.42 | −0.25 | 0.81 | <0.01 | 1.42 | 0.01 | 1.00 |
Hemoglobin A1c, % | −0.14 | 1.57 | −1.90 | 0.06 | −0.06 | 1.57 | −0.75 | 0.45 |
Men | −0.09 | 1.27 | −1.30 | 0.20 | 0.04 | 1.27 | 0.57 | 0.57 |
Three or more kinds of antihypertensive drugs | −0.01 | 1.18 | −0.15 | 0.88 | <0.01 | 1.18 | 0.04 | 0.96 |
Lipid-lowering drug treatment | 0.08 | 1.47 | 1.13 | 0.26 | −0.01 | 1.46 | −0.09 | 0.93 |
Antidiabetic drug treatment | −0.06 | 1.64 | −0.77 | 0.44 | −0.06 | 1.64 | −0.75 | 0.45 |
Past CVD | 0.10 | 1.44 | 1.31 | 0.19 | 0.17 | 1.45 | −2.38 | 0.02 |
Current smoking | −0.03 | 1.18 | 0.47 | 0.64 | 0.06 | 1.17 | 0.97 | 0.33 |
Log TMAO | −0.04 | 1.23 | −0.63 | 0.53 | <0.01 | 1.18 | −0.04 | 0.96 |