Fig. 1 | Hypertension Research

Fig. 1

From: Goreisan attenuates cardiac hypertrophy and diastolic dysfunction in heart failure with preserved ejection fraction induced by HFD/L-NAME via regulation of ICAT-β-catenin/ERK axis

Fig. 1

GRS suppressed cardiac hypertrophy and reduced pulmonary congestion in HFpEF mice. A–F Body weight, systolic and diastolic blood pressure, heart rate, blood glucose, and total cholesterol in mice fed normal diet, normal diet+GRS, HFD/L-NAME, or HFD/L-NAME + GRS for 5 weeks (n = 5–12). G, H Ratios of whole heart (WH) weight to tibial length (TL) and left ventricle (LV) weight to TL the indicated groups (n = 12–21). I Ratio of wet lung weight to dry lung weight in the indicated groups (n = 5–6). J, K Extracellular volume (ECV) and plasma volume (PV) adjusted for TL in the indicated groups (n = 9–11). L Ratio of ECV to PV in the indicated groups (n = 9–11). P < 0.05, **P < 0.01: post-hoc Tukey’s comparison test

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