Table 1 Baseline characteristics of the matched group

From: Carotid pulsatile energy fraction surpasses traditional hemodynamic markers in explaining cognitive impairment among hemodialysis patients

Variables

Hemodialysis

Community

SMD

Mean (SD), n (%), or median (IQR)

Group

Group

N

130

456

 

Age (years)a

64.5 (11.7)

64.3 (10.5)

0.020

Male, n (%)a

78 (60)

243 (53)

0.138

Education level, n (%)a

  

0.172

 Elementary school/below

20 (15)

71 (16)

 

 Junior school

32 (25)

82 (18)

 

 High school

50 (38)

129 (28)

 

 University or higher

28 (22)

174 (38)

 

Clinical characteristics

   

BMI, kg/m2

23.9 (3.5)

24.1 (3.2)

0.054

Hemodialysis duration, y

4.6 (1.2, 4.6)

  

Medical history, n (%)

   

 Hypertension

110 (85)

186 (41)

1.064

 Diabetes mellitus

72 (55)

60 (13)

1.024

Biochemistry data

   

 Cholesterol, mg/dl

149.1 (37.4)

199.7 (36.5)

1.357

 Albumin, g/dl

3.9 (0.25)

NA

 

 Calcium x Phosphate

49.4 (14.3)

NA

 

 Kt/V

1.61 (0.24)

NA

 

Medications, n (%)

   

 Antiplatelet

23 (18)

NA

 

 Statin

48 (37)

NA

 

 RAI

47 (36)

NA

 

 CCB

49 (38)

NA

 

Brachial BP

   

 Systolic BP, mmHg

133.7 (26.6)

129.3 (17.7)

0.197

 Diastolic BP, mmHg

74.9 (15.1)

76.2 (9.8)

0.105

 Pulse pressure, mmHg

58.9 (17.2)

53.1 (13.3)

0.389

 Heart rate, /min

72.1 (21.9)

68.6 (12.6)

0.201

Blood vessel function

  

 cfPWV, m/sec

13.5 (5.9)

13.5 (3.9)

0.002

 Zao, dyne*s/cm5

261.1 (178.7)

128.7 (61.9)

0.99

 Zca, dyne*s/cm5

1325.5 (605.4)

1211 (523.2)

0.196

Cognitive function

  

0.134

 Cognitive dysfunction, n (%)

51 (39)

151 (33)

 

 MoCA score, median (IQR)

26 (24, 29)

27 (25, 28)

0.075

  1. Values are expressed by n (%), mean (SD), or median (IQR) as appropriate
  2. Data are from the hemodialysis participants who completed hemodynamic assessment (n = 162)
  3. Of these, 152 completed cognitive testing and are analyzed in Tables 3 and 4
  4. BP blood pressure, cf-PWV carotid-femoral pulse wave velocity, Kt/V urea clearance, Zao Aortic characteristic impedance, Zca Carotid characteristic impedance, MoCA Montreal Cognitive Assessment; Cognitive dysfunction: MoCA score < 26, SMD standardized mean difference
  5. aVariables included in the propensity score (PS) model