Fig. 11

Changes in left cardiac functions (assessed by invasive hemodynamic analysis) from the transition phase (two weeks after ACF creation, data taken from the current study) to the decompensation phase (three weeks after ACF creation, data taken from the reference #37). Changes are expressed as percent increases in hypertensive Ren-2 transgenic (TGR) rats with ACF compared to sham-operated TGR at the same time. Changes are shown in left ventricle peak pressure A, maximum rates of pressure rise ( + dP/dt)max B, end-systolic pressure volume relationship (ESPVR) C, preload recruitable stroke work D, left ventriculo-arterial coupling E and left ventricular efficiency F. * P < 0.05 compared with ACF TGR two weeks after ACF induction