Fig. 6

Representative histological images of the left ventricle. Sections are stained with Picrosirius Red (200x), in these bright-field microscopy images, the collagen is red against a pale-yellow background. The scale bar in the figure is 100 µm. A sham-operated normotensive transgene-negative Hannover Sprague-Dawley rats (HanSD) (average fibrosis in this group is 1.57 ± 0.11%), B hypertensive sham-operated Ren-2 transgenic (TGR) rats (average fibrosis in this group is 1.70 ± 0.18%) and C in TGR two weeks after creation of the aorto-caval fistula (ACF) (average fibrosis in this group is 2.83 ± 0.26%)