Table 1 Baseline clinical characteristics of chronological age groups

From: The modifying effect of chronological age on the predictive value of vascular aging indicators for the long-term cardiovascular events risk

Variables

Overall Population (n = 8163)

<60 years (n = 5691)

≥60 years (n = 2472)

P Value

Chronological age, year

55.0 (50.5–61.0)

53.0 (49.0–56.0)

66.0 (62.0–72.0)

<0.001

Vascular age, year

55.6 (52.2–60.4)

53.8 (51.1–57.0)

61.8 (57.7–66.3)

<0.001

∆-age, year

−0.26 (−3.0 to 2.8)

−0.36 (−2.9 to 2.5)

0.10 (−3.3 to 3.8)

0.005

Male, n (%)

2888 (35.4)

1861 (32.7)

1027 (41.5)

<0.001

BMI, kg/m2

25.8 (23.6–28.1)

25.8 (23.6–28.0)

25.9 (23.6–28.2)

0.308

WC, cm

82 (77–88)

82 (76–87)

84 (79–90)

<0.001

Current smoking, n (%)

1551 (19.0)

1197 (21.0)

354 (14.3)

<0.001

SBP, mmHg

131.3 (121.3–143.0)

128.7 (119.7–139.7)

137.7 (127.7–149.7)

<0.001

DBP, mmHg

74.3 (68.0–81.0)

75.3 (69.0–82.0)

72.0 (65.3–79.0)

<0.001

Heart rate, bpm

77.7 (70.7–85.0)

77.3 (70.7–84.7)

78.0 (70.6–85.7)

0.11

TC, mmol/L

5.3 (4.7–5.9)

5.3 (4.7–5.9)

5.3 (4.6–6.0)

0.929

TG, mmol/L

1.3 (0.9–1.9)

1.3 (0.9–1.9)

1.3 (1.0–1.8)

0.378

HDL-C, mmol/L

1.4 (1.2–1.7)

1.4 (1.2–1.7)

1.4 (1.2–1.7)

0.839

LDL-C, mmol/L

3.2 (2.7–3.8)

3.2 (2.7–3.8)

3.3 (2.7–3.8)

0.186

FBG, mmol/L

5.6 (5.2–6.3)

5.6 (5.2–6.2)

5.8 (5.4–6.7)

<0.001

eGFR, mL/min/1.73 m2

97.4 (88.1–103.7)

101.0 (95.0–105.8)

87.6 (77.7–93.8)

<0.001

Hypertension, n (%)

3872 (47.4)

2236 (39.3)

1636 (66.2)

<0.001

Diabetes, n (%)

1930 (23.6)

1091 (19.2)

839 (33.9)

<0.001

Dyslipidemia, n (%)

5790 (70.9)

3965 (69.7)

1825 (73.8)

<0.001

Anti-hypertensive medications, n (%)

2415 (29.6)

1312 (23.1)

1103 (44.6)

<0.001

Anti-diabetes medications, n (%)

794 (9.7)

416 (7.3)

378 (15.3)

<0.001

Lipid-lowering medications, n (%)

725 (8.9)

398 (7.0)

327 (13.2)

<0.001

CVD risk, %

5.2 (2.6–10.3)

3.6 (2.0–6.7)

11.4 (7.2–17.2)

<0.001

baPWV, m/s

15.7 (13.9–18.2)

14.9 (13.4–16.8)

18.4 (16.1–21.2)

<0.001

  1. Data were presented as median (IQR) or n (%) of the group. ∆-age indicates the residuals by regressing vascular age on chronological age
  2. BMI body mass index, WC waist circumference, SBP systolic blood pressure, DBP diastolic blood pressure, TC total cholesterol, TG triglycerides, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, FBG fasting blood glucose, eGFR estimated glomerular filtration rate, CVD risk risk of cardiovascular disease estimated by China-PAR model, baPWV brachial-ankle pulse wave velocity
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