Table 1 Characteristics of the study population and groups of normal cognitive function and suspected MCI
Total (n = 1423) | Normal (n = 945) | Suspected MCI (n = 478) | P value | |
|---|---|---|---|---|
Age | 59.8 ± 11.8 | 59.3 ± 11.2 | 60.8 ± 12.8 | 0.064 |
Gender (male, %) | 667(46.9) | 445(47.1) | 222(46.5) | 0.830 |
Education levels (n, %) | 0.010 | |||
No | 19(1.3) | 6(0.6) | 13(2.7) | |
Elementary school | 225(15.8) | 151(16.0) | 74(15.5) | |
Junior school | 186(13.1) | 104(11.0) | 82(17.2) | |
High school | 455(32.0) | 313(33.1) | 142(29.7) | |
University or higher | 538(37.8) | 371(39.3) | 167(34.9) | |
Hypertension (n, %) | 442(31.1) | 281(29.7) | 161(33.7) | 0.130 |
Diabetes mellitus (n, %) | 210(14.8) | 138(14.6) | 72(15.1) | 0.810 |
Smoking (n, %) | ||||
non-smoker | 1052(73.9) | 697(73.8) | 355(74.3) | 0.860 |
previous smoker | 227(16.0) | 156(16.5) | 71(14.9) | |
current smoker | 144(10.1) | 92(9.7) | 52(10.9) | |
BMI | 24.64 ± 3.49 | 24.63 ± 3.45 | 24.66 ± 3.57 | 0.946 |
Creatinine (mg/dL) | 0.8 ± 0.36 | 0.79 ± 0.31 | 0.83 ± 0.45 | 0.229 |
Glucose (mg/dL) | 101.28 ± 23.94 | 101.32 ± 24.17 | 101.21 ± 23.53 | 0.860 |
LDL (mg/dL) | 117.53 ± 35.55 | 117.33 ± 35.20 | 117.93 ± 36.25 | 0.787 |
Triglyceride (mg/dL) | 127.11 ± 80.79 | 126.97 ± 72.94 | 127.37 ± 94.46 | 0.340 |
MAP (mmHg) | 91.91 ± 13.38 | 91.88 ± 13.07 | 91.97 ± 13.97 | 0.604 |
HR (beat/min) | 67.13 ± 10.24 | 67.01 ± 10.23 | 67.36 ± 10.25 | 0.566 |
Carotid SBP (mmHg) | 115.41 ± 16.71 | 115.03 ± 16.71 | 116.16 ± 16.71 | 0.288 |
Carotid PP (mmHg) | 39.07 ± 9.91 | 38.64 ± 9.59 | 39.93 ± 10.47 | 0.044 |
Index of aortic stiffness | ||||
Zc (dyne·s/cm5) | 96.66 ± 39.18 | 94.25 ± 39.22 | 101.42 ± 38.7 | <0.001 |
Indices of carotid stiffness | ||||
CCI (dyne·s/cm5) | 3138.1 ± 1262.78 | 3073.1 ± 1209.20 | 3266.7 ± 1354.67 | 0.019 |
CS (%) | 5.84 ± 2.66 | 5.82 ± 2.57 | 5.88 ± 2.82 | 0.941 |
CC (mm2/kPa) | 0.65 ± 0.31 | 0.65 ± 0.31 | 0.64 ± 0.32 | 0.422 |
DC (10−3/kPa) | 24.42 ± 12.66 | 24.45 ± 11.95 | 24.36 ± 13.99 | 0.257 |
YEM (103/kPa) | 0.51 ± 0.36 | 0.49 ± 0.31 | 0.54 ± 0.43 | 0.375 |
β | 8.45 ± 4.86 | 8.28 ± 4.56 | 8.80 ± 5.40 | 0.332 |
Diameter (mm) | 6.3 ± 0.70 | 6.3 ± 0.70 | 6.3 ± 0.80 | 0.379 |
IMT (mm) | 0.75 ± 0.38 | 0.75 ± 0.40 | 0.76 ± 0.32 | 0.266 |
CIRa | 3.48 ± 0.49 | 3.49 ± 0.50 | 3.46 ± 0.47 | 0.402 |
