Extended Data Fig. 1: Canonical function of the bifunctional enzyme 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II in plants.
From: VC1 catalyses a key step in the biosynthesis of vicine in faba bean

(a) Domain structure. The protein is composed of a chloroplast targeting peptide (cTP) fused to two catalytic domains: the 3,4-dihydroxy-2-butanone-4-phosphate synthase domain, also called RibB, and the GTP cyclohydrolase II domain, also called RibA. (b) Biochemical function of each catalytic domain in the context of the riboflavin biosynthesis pathway.